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HEALTH: The Dangerous Relationship Between Obesity and HIV

(GayWebSource.com - Gay News & Press Network) - Posted by Jake Simpson - TheGayUK.com

The Dangerous Relationship Between Obesity and HIV

by Doctor Clovis Palmer

According to recent data from the SUN (Study to Understand the Natural History of HIV and AIDS in the Era of Effective Therapy), which includes 494 patients, approximately 61% were either overweight or obese. Obesity was associated with insulin resistance, elevated cholesterol, increased inflammation and atherosclerosis.

A reduction of dietary intake of 500 calories per day for 8 weeks resulted in a 6% decrease in body weight. What was remarkable in this study was the dramatic decline in systemic inflammation observed in the study participants. Indeed, two reputable markers of inflammation, tumour necrosis factor (TNF) and C-reactive protein, were reduced by almost 50% in only 8 weeks of calorie reduction.

Inflammatory diseases such as diabetes, cardiovascular disease (CVD), kidney problems, osteoporosis, cogitative impairment and fragility, are becoming increasingly common in people living with HIV. As the prevalence of obesity and HIV-associated co-morbidities continues to rise, and concerns for the spiralling economic and social costs escalate, innovative management strategies beyond primary care are urgently needed. Many traditional lifestyle interventions can be implemented with the assistance of professionals, including:

• Maintain a maximal viral suppression with antiretroviral therapy

• Reduce or stop smoking

• Lose at least 5-10% of body weight (if overweight)

• Exercise

• Consume more fruits and vegetables

• Reduce alcohol intake

One reason why people who are infected with HIV have high levels of inflammation is that HIV destroys the structure of the intestine (gut), causing bad bacteria to strive, and changes the dynamics of the gut microbiota.

Toxins produced by bad bacteria cross the wall of the intestine and into the blood stream to instigate and fuel inflammation, and cause age-associated diseases. Similarly, alterations of the gut microbiota and mucosal barrier have been identified as a novel CVD risk factor and are associated with metabolic diseases such as obesity and type 2 diabetes.

Incredibly, probiotic treatment using Bifidobacterium animalis ssp. lactis 420 has shown great promise in reducing body weight and liver inflammation in animal models.

The increasing prevalence of obesity and type 2 diabetes demonstrates the difficulties of conventional treatments and interventions to curb these diseases. Efforts to identify new therapeutic strategies to modulate gut microbiota are now a high priority for public health and, to date, probiotics and/or prebiotics seem to be the most effective tools.

Diet, especially high intake of fermentable fibres and plant polyphenols, appears to regulate microbial activities within the gut, supporting regulatory guidelines that encourage increased consumption of whole-plant foods (fruit, vegetables and whole-grain cereals) and providing the scientific rationale for the design of efficacious prebiotics.

Polyphenol-rich cranberry extract has been proven to protect mice from diet-induced obesity and insulin resistance, although the effect might have been mediated by the regulation of intestinal inflammation. Recent human studies with carefully selected probiotic strains have shown that ingestion of viable micro-organisms with the ability to hydrolyse bile salts could lower blood cholesterol, a recognised risk factor in obesity-related CVD.

1. Overton ET. Metabolic complications of HIV infection and its therapies. Top Antivir Med 2014,22:651-654.

2. Palmer CS. Inflammation speeds up the aging process in people infected with HIV, 2014, http://www.naturalimmunity.com.au/hiv.html#B.

3. Palmer CS, Crowe SM. How does monocyte metabolism impact inflammation and aging during chronic HIV infection? AIDS Res Hum Retroviruses 2014,30:335-336.

4. Stenman LK, Waget A, Garret C, Klopp P, Burcelin R, Lahtinen S. Potential probiotic Bifidobacterium animalis ssp. lactis 420 prevents weight gain and glucose intolerance in diet-induced obese mice. Benef Microbes 2014,5:437-445.

Dr Clovis Palmer is a graduate of the University of Sydney, Australia, and holds a PhD in plant biochemistry and molecular genetics. He conducted postdoctoral studies in immunology, liver disease and obesity at the University of New South Wales, Australia.

Dr Palmer is a reviewer for several top ranked international journals including Hepatology, AIDS and Antioxidants and Redox Signalling. He is the chief scientific editor for Natural Immunity-Health, Australia (www.naturalimmunity.com.au).

How To Fight Obesity Naturally

Gay Men Bucking Downward Trend In New HIV Infections

STIs, HIV and AIDS To Be Discussed In Secondary Education

Media Provided by the GayWebSource.com - Gay News & Press Network.
To republish this post please visit HEALTH: The Dangerous Relationship Between Obesity and HIV

HEALTH: The Dangerous Relationship Between Obesity and HIV

(GayWebSource.com - Gay News & Press Network) - Posted by Jake Simpson - TheGayUK.com

The Dangerous Relationship Between Obesity and HIV

by Doctor Clovis Palmer

According to recent data from the SUN (Study to Understand the Natural History of HIV and AIDS in the Era of Effective Therapy), which includes 494 patients, approximately 61% were either overweight or obese. Obesity was associated with insulin resistance, elevated cholesterol, increased inflammation and atherosclerosis.

A reduction of dietary intake of 500 calories per day for 8 weeks resulted in a 6% decrease in body weight. What was remarkable in this study was the dramatic decline in systemic inflammation observed in the study participants. Indeed, two reputable markers of inflammation, tumour necrosis factor (TNF) and C-reactive protein, were reduced by almost 50% in only 8 weeks of calorie reduction.

Inflammatory diseases such as diabetes, cardiovascular disease (CVD), kidney problems, osteoporosis, cogitative impairment and fragility, are becoming increasingly common in people living with HIV. As the prevalence of obesity and HIV-associated co-morbidities continues to rise, and concerns for the spiralling economic and social costs escalate, innovative management strategies beyond primary care are urgently needed. Many traditional lifestyle interventions can be implemented with the assistance of professionals, including:

• Maintain a maximal viral suppression with antiretroviral therapy

• Reduce or stop smoking

• Lose at least 5-10% of body weight (if overweight)

• Exercise

• Consume more fruits and vegetables

• Reduce alcohol intake

One reason why people who are infected with HIV have high levels of inflammation is that HIV destroys the structure of the intestine (gut), causing bad bacteria to strive, and changes the dynamics of the gut microbiota.

Toxins produced by bad bacteria cross the wall of the intestine and into the blood stream to instigate and fuel inflammation, and cause age-associated diseases. Similarly, alterations of the gut microbiota and mucosal barrier have been identified as a novel CVD risk factor and are associated with metabolic diseases such as obesity and type 2 diabetes.

Incredibly, probiotic treatment using Bifidobacterium animalis ssp. lactis 420 has shown great promise in reducing body weight and liver inflammation in animal models.

The increasing prevalence of obesity and type 2 diabetes demonstrates the difficulties of conventional treatments and interventions to curb these diseases. Efforts to identify new therapeutic strategies to modulate gut microbiota are now a high priority for public health and, to date, probiotics and/or prebiotics seem to be the most effective tools.

Diet, especially high intake of fermentable fibres and plant polyphenols, appears to regulate microbial activities within the gut, supporting regulatory guidelines that encourage increased consumption of whole-plant foods (fruit, vegetables and whole-grain cereals) and providing the scientific rationale for the design of efficacious prebiotics.

Polyphenol-rich cranberry extract has been proven to protect mice from diet-induced obesity and insulin resistance, although the effect might have been mediated by the regulation of intestinal inflammation. Recent human studies with carefully selected probiotic strains have shown that ingestion of viable micro-organisms with the ability to hydrolyse bile salts could lower blood cholesterol, a recognised risk factor in obesity-related CVD.

1. Overton ET. Metabolic complications of HIV infection and its therapies. Top Antivir Med 2014,22:651-654.

2. Palmer CS. Inflammation speeds up the aging process in people infected with HIV, 2014, http://www.naturalimmunity.com.au/hiv.html#B.

3. Palmer CS, Crowe SM. How does monocyte metabolism impact inflammation and aging during chronic HIV infection? AIDS Res Hum Retroviruses 2014,30:335-336.

4. Stenman LK, Waget A, Garret C, Klopp P, Burcelin R, Lahtinen S. Potential probiotic Bifidobacterium animalis ssp. lactis 420 prevents weight gain and glucose intolerance in diet-induced obese mice. Benef Microbes 2014,5:437-445.

Dr Clovis Palmer is a graduate of the University of Sydney, Australia, and holds a PhD in plant biochemistry and molecular genetics. He conducted postdoctoral studies in immunology, liver disease and obesity at the University of New South Wales, Australia.

Dr Palmer is a reviewer for several top ranked international journals including Hepatology, AIDS and Antioxidants and Redox Signalling. He is the chief scientific editor for Natural Immunity-Health, Australia (www.naturalimmunity.com.au).

How To Fight Obesity Naturally

Gay Men Bucking Downward Trend In New HIV Infections

STIs, HIV and AIDS To Be Discussed In Secondary Education

Media Provided by the GayWebSource.com - Gay News & Press Network.
To republish this post please visit HEALTH: The Dangerous Relationship Between Obesity and HIV

HEALTH: The Dangerous Relationship Between Obesity and HIV

(GayWebSource.com - Gay News & Press Network) - Posted by Jake Simpson - TheGayUK.com

The Dangerous Relationship Between Obesity and HIV

by Doctor Clovis Palmer

According to recent data from the SUN (Study to Understand the Natural History of HIV and AIDS in the Era of Effective Therapy), which includes 494 patients, approximately 61% were either overweight or obese. Obesity was associated with insulin resistance, elevated cholesterol, increased inflammation and atherosclerosis.

A reduction of dietary intake of 500 calories per day for 8 weeks resulted in a 6% decrease in body weight. What was remarkable in this study was the dramatic decline in systemic inflammation observed in the study participants. Indeed, two reputable markers of inflammation, tumour necrosis factor (TNF) and C-reactive protein, were reduced by almost 50% in only 8 weeks of calorie reduction.

Inflammatory diseases such as diabetes, cardiovascular disease (CVD), kidney problems, osteoporosis, cogitative impairment and fragility, are becoming increasingly common in people living with HIV. As the prevalence of obesity and HIV-associated co-morbidities continues to rise, and concerns for the spiralling economic and social costs escalate, innovative management strategies beyond primary care are urgently needed. Many traditional lifestyle interventions can be implemented with the assistance of professionals, including:

• Maintain a maximal viral suppression with antiretroviral therapy

• Reduce or stop smoking

• Lose at least 5-10% of body weight (if overweight)

• Exercise

• Consume more fruits and vegetables

• Reduce alcohol intake

One reason why people who are infected with HIV have high levels of inflammation is that HIV destroys the structure of the intestine (gut), causing bad bacteria to strive, and changes the dynamics of the gut microbiota.

Toxins produced by bad bacteria cross the wall of the intestine and into the blood stream to instigate and fuel inflammation, and cause age-associated diseases. Similarly, alterations of the gut microbiota and mucosal barrier have been identified as a novel CVD risk factor and are associated with metabolic diseases such as obesity and type 2 diabetes.

Incredibly, probiotic treatment using Bifidobacterium animalis ssp. lactis 420 has shown great promise in reducing body weight and liver inflammation in animal models.

The increasing prevalence of obesity and type 2 diabetes demonstrates the difficulties of conventional treatments and interventions to curb these diseases. Efforts to identify new therapeutic strategies to modulate gut microbiota are now a high priority for public health and, to date, probiotics and/or prebiotics seem to be the most effective tools.

Diet, especially high intake of fermentable fibres and plant polyphenols, appears to regulate microbial activities within the gut, supporting regulatory guidelines that encourage increased consumption of whole-plant foods (fruit, vegetables and whole-grain cereals) and providing the scientific rationale for the design of efficacious prebiotics.

Polyphenol-rich cranberry extract has been proven to protect mice from diet-induced obesity and insulin resistance, although the effect might have been mediated by the regulation of intestinal inflammation. Recent human studies with carefully selected probiotic strains have shown that ingestion of viable micro-organisms with the ability to hydrolyse bile salts could lower blood cholesterol, a recognised risk factor in obesity-related CVD.

1. Overton ET. Metabolic complications of HIV infection and its therapies. Top Antivir Med 2014,22:651-654.

2. Palmer CS. Inflammation speeds up the aging process in people infected with HIV, 2014, http://www.naturalimmunity.com.au/hiv.html#B.

3. Palmer CS, Crowe SM. How does monocyte metabolism impact inflammation and aging during chronic HIV infection? AIDS Res Hum Retroviruses 2014,30:335-336.

4. Stenman LK, Waget A, Garret C, Klopp P, Burcelin R, Lahtinen S. Potential probiotic Bifidobacterium animalis ssp. lactis 420 prevents weight gain and glucose intolerance in diet-induced obese mice. Benef Microbes 2014,5:437-445.

Dr Clovis Palmer is a graduate of the University of Sydney, Australia, and holds a PhD in plant biochemistry and molecular genetics. He conducted postdoctoral studies in immunology, liver disease and obesity at the University of New South Wales, Australia.

Dr Palmer is a reviewer for several top ranked international journals including Hepatology, AIDS and Antioxidants and Redox Signalling. He is the chief scientific editor for Natural Immunity-Health, Australia (www.naturalimmunity.com.au).

How To Fight Obesity Naturally

Gay Men Bucking Downward Trend In New HIV Infections

STIs, HIV and AIDS To Be Discussed In Secondary Education

Media Provided by the GayWebSource.com - Gay News & Press Network.
To republish this post please visit HEALTH: The Dangerous Relationship Between Obesity and HIV

East Coachella Valley Youth Research Project Consultant

(GayWebSource.com - Gay News & Press Network) - Posted by SeasonsofPride.com

Gay-Straight Alliance NetworkMecca, CA

GSA Network seeks an independent consultant in the East Coachella Valley (ECV) area to identify, engage, coordinate, and lead a youth-led participatory action research project (YPAR) that will assist in the community in gaining knowledge and understanding of LGBTQ youth experience and cultural sensitivities. Funded by The California Endowment and working with GSA Network, with the support of UC Davis Center for Regional Change (UCDCRC) and community stakeholders, the ECV Youth Research Consultant will engage community advisory group made up of EVC Building Healthy Communities (ECVBHC) staff, Boys and Men of Color (BMOC) Coordinator, Girls and Women of Color (GWOC) Coordinator, the Youth Research Consultant will lead youth through the developmental, implementation and analysis stages of a community needs assessment. The project seeks to gather information on: unique community health priorities and needs of LGBTQ youth of ECV; support, services, and resources available to youth through grassroots, not-profit and public organizations; and community health priorities in alignment with BMOC and GWOC initiatives in ECV. The work will conclude with a final report, including a short executive summary or brief documenting the YPAR findings. This project is anticipated to be a two-year (part-time) project that will begin at time of hire.

East Coachella Valley Youth Research Project Consultant

East Coachella Valley Youth Research Project Consultant

GSA Network is guided by our vision of full equality and social justice for all LGBTQ people. We have developed a model of grassroots organizing that trains youth activists to understand and challenge multiple systems of oppressions, in order to develop LGBTQ and allied leaders with a vision for broad social justice. Grounded in this model, GSA Network is building the GSA movement by providing resources, training, and grassroots organizing support to GSA clubs working to educate schools about LGBT issues and change public policy as well as to emerging GSA Networks in states around the U.S. As leader of the National Association of GSA Networks we bring together youth and adult leaders from state and regional GSA Networks to share best practices for GSA organizing. As a national leader in the LGBT, safe schools, and education justice movements, this is an exciting time for GSA Network as we expand our impact in California and nationally, and grow our team. You can learn more about our work at www.gsanetwork.org.

Principal Responsibilities

  • Engage a community advisory group made up of: ECVBHC, BMOC Coordinator, GWOC Coordinator, and other relevant community stakeholders to ground the YPAR project in the context of the BHC and broader ECV community
  • Recruit and lead youth through the developmental implementation and analysis stages of the YPAR project to identify: unique community health priorities and needs of LGBTQ youth of ECV; support, services, and resources available to youth through grassroots, not-profit and public organizations; and community health priorities
  • Recruit youth, parents, community stakeholders, and school administrators/faculty/staff to host a community forum, including identifying speakers and presenters, led by youth
  • Draft and develop final report to document finding, including a short executive summary or brief
  • Work with UCDCRC on strategic design, planning, and development of the project, including methodological aspects of strategy, goals and outcomes selection, implementation strategies, and post-project action plan development (year 2)
    • Participate in UCDCRC’s training, orientation, and coaching on the Stepping Stones Curriculum and PYOM mapping tools.
    • Work with and meet with UCDCRC to ensure progress of the work through regular communication, exchanges, and status reports. Participate in bi-monthly Advisory Committee conference calls to engage in project updates and status reports
    • Visit other BHC sites to gain knowledge and understanding of best practices for incorporating LGBTQ youth needs

Qualifications:

  • Two years experience working collaboratively with multiple stakeholders from youth, parents, funders, academics, non-profit stakeholders, and researchers
  • Deep knowledge of the East Coachella Valley and cursory needs of LGBTQ youth. Knowledge of health/mental health needs a plus.
  • Ability to recruit, lead, facilitate a group of youth participants in youth-led participatory action research
  • Excellent writing and strategic communication skills. Additional language skill pertinent to the ECV area a plus
  • Highly intelligent, with the ability to think and act quickly and strategically
  • Excellent attention to detail and accuracy
  • Proven ability to work with efficiency, flexibility, and good humor
  • Ability to manage multiple priorities and projects effectively, independently and collaboratively
  • Experience as a participant, leader, or facilitator in youth-led participatory action research projects, a plus
  • Demonstrated commitment to social justice, anti-oppression work, and LGBTQ rights.
  • Demonstrated ability to work as part of a team and with people from a variety of different racial, ethnic, socioeconomic, educational, religious, sexual, gender, and generational backgrounds

Send cover letter and resume to ECVConsultant@gsanetwork.org or to GSA Network, 1550 Bryant Street #600, San Francisco, CA 94103. Please include ECV Project Consultant in the subject heading of your email. No phone calls or faxes please. Only those applicants selected for an interview will receive a response.

Equal Opportunity Employer

GSA Network is an equal opportunity employer and encourages applications from youth, people of color, people of all sexual orientations and gender identities, and people with disabilities.

The post East Coachella Valley Youth Research Project Consultant appeared first on Seasons of Pride.

Media Provided by the GayWebSource.com - Gay News & Press Network.
To republish this post please visit East Coachella Valley Youth Research Project Consultant

East Coachella Valley Youth Research Project Consultant

(GayWebSource.com - Gay News & Press Network) - Posted by SeasonsofPride.com

Gay-Straight Alliance NetworkMecca, CA

GSA Network seeks an independent consultant in the East Coachella Valley (ECV) area to identify, engage, coordinate, and lead a youth-led participatory action research project (YPAR) that will assist in the community in gaining knowledge and understanding of LGBTQ youth experience and cultural sensitivities. Funded by The California Endowment and working with GSA Network, with the support of UC Davis Center for Regional Change (UCDCRC) and community stakeholders, the ECV Youth Research Consultant will engage community advisory group made up of EVC Building Healthy Communities (ECVBHC) staff, Boys and Men of Color (BMOC) Coordinator, Girls and Women of Color (GWOC) Coordinator, the Youth Research Consultant will lead youth through the developmental, implementation and analysis stages of a community needs assessment. The project seeks to gather information on: unique community health priorities and needs of LGBTQ youth of ECV; support, services, and resources available to youth through grassroots, not-profit and public organizations; and community health priorities in alignment with BMOC and GWOC initiatives in ECV. The work will conclude with a final report, including a short executive summary or brief documenting the YPAR findings. This project is anticipated to be a two-year (part-time) project that will begin at time of hire.

East Coachella Valley Youth Research Project Consultant

East Coachella Valley Youth Research Project Consultant

GSA Network is guided by our vision of full equality and social justice for all LGBTQ people. We have developed a model of grassroots organizing that trains youth activists to understand and challenge multiple systems of oppressions, in order to develop LGBTQ and allied leaders with a vision for broad social justice. Grounded in this model, GSA Network is building the GSA movement by providing resources, training, and grassroots organizing support to GSA clubs working to educate schools about LGBT issues and change public policy as well as to emerging GSA Networks in states around the U.S. As leader of the National Association of GSA Networks we bring together youth and adult leaders from state and regional GSA Networks to share best practices for GSA organizing. As a national leader in the LGBT, safe schools, and education justice movements, this is an exciting time for GSA Network as we expand our impact in California and nationally, and grow our team. You can learn more about our work at www.gsanetwork.org.

Principal Responsibilities

  • Engage a community advisory group made up of: ECVBHC, BMOC Coordinator, GWOC Coordinator, and other relevant community stakeholders to ground the YPAR project in the context of the BHC and broader ECV community
  • Recruit and lead youth through the developmental implementation and analysis stages of the YPAR project to identify: unique community health priorities and needs of LGBTQ youth of ECV; support, services, and resources available to youth through grassroots, not-profit and public organizations; and community health priorities
  • Recruit youth, parents, community stakeholders, and school administrators/faculty/staff to host a community forum, including identifying speakers and presenters, led by youth
  • Draft and develop final report to document finding, including a short executive summary or brief
  • Work with UCDCRC on strategic design, planning, and development of the project, including methodological aspects of strategy, goals and outcomes selection, implementation strategies, and post-project action plan development (year 2)
    • Participate in UCDCRC’s training, orientation, and coaching on the Stepping Stones Curriculum and PYOM mapping tools.
    • Work with and meet with UCDCRC to ensure progress of the work through regular communication, exchanges, and status reports. Participate in bi-monthly Advisory Committee conference calls to engage in project updates and status reports
    • Visit other BHC sites to gain knowledge and understanding of best practices for incorporating LGBTQ youth needs

Qualifications:

  • Two years experience working collaboratively with multiple stakeholders from youth, parents, funders, academics, non-profit stakeholders, and researchers
  • Deep knowledge of the East Coachella Valley and cursory needs of LGBTQ youth. Knowledge of health/mental health needs a plus.
  • Ability to recruit, lead, facilitate a group of youth participants in youth-led participatory action research
  • Excellent writing and strategic communication skills. Additional language skill pertinent to the ECV area a plus
  • Highly intelligent, with the ability to think and act quickly and strategically
  • Excellent attention to detail and accuracy
  • Proven ability to work with efficiency, flexibility, and good humor
  • Ability to manage multiple priorities and projects effectively, independently and collaboratively
  • Experience as a participant, leader, or facilitator in youth-led participatory action research projects, a plus
  • Demonstrated commitment to social justice, anti-oppression work, and LGBTQ rights.
  • Demonstrated ability to work as part of a team and with people from a variety of different racial, ethnic, socioeconomic, educational, religious, sexual, gender, and generational backgrounds

Send cover letter and resume to ECVConsultant@gsanetwork.org or to GSA Network, 1550 Bryant Street #600, San Francisco, CA 94103. Please include ECV Project Consultant in the subject heading of your email. No phone calls or faxes please. Only those applicants selected for an interview will receive a response.

Equal Opportunity Employer

GSA Network is an equal opportunity employer and encourages applications from youth, people of color, people of all sexual orientations and gender identities, and people with disabilities.

The post East Coachella Valley Youth Research Project Consultant appeared first on Seasons of Pride.

Media Provided by the GayWebSource.com - Gay News & Press Network.
To republish this post please visit East Coachella Valley Youth Research Project Consultant